A new method to mine existing scientific data may provide a wealth of information about the interactions among genes, the environment and biological processes, say researchers at the Stanford University School of Medicine, Lucile Packard Childrens Hospital and Harvard Medical School. Like panning for gold, they used the powerful technique to sift through millions of bits of unrelated information - in this case, gene expression data from so-called microarray experiments - to pinpoint genes likely to be involved in leukemia, aging, injury and muscle development.
"This is just the tip of the iceberg," said bioinformatics specialist Atul Butte, MD, PhD, who is also a pediatrician at Lucile Packard Childrens Hospital at Stanford. "Nearly 100 different diseases have been studied using microarrays, spanning all of medicine. This is a new way to explore this type of data. We can study virtually everything thats been studied." Butte is the first author of the study, which is published in the Jan. 6 online issue of Nature Biotechnology.
The advance comes with a caveat, however: clinically useful nuggets will be buried under the avalanche of data inundating international repositories each year unless scientists come up with a way to better classify their experiments and results.
Closing in on advanced prostate cancer
13.12.2017 | Institute for Research in Biomedicine (IRB Barcelona)
Visualizing single molecules in whole cells with a new spin
13.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
13.12.2017 | Health and Medicine
13.12.2017 | Physics and Astronomy
13.12.2017 | Life Sciences