Sequencers expose secret chromosome centre.
Stuck in the middle: centromeres repeats had the sequencers foxed.
H. Willard et al.
Februarys celebrations hid a dark secret: the human genome sequencers hadnt touched the hearts of our chromosomes. Now, at last, one chromosomes inscrutable midpoint, its centromere, has given up its genetic secrets.
Centromeres look like the waist in an X. They share out chromosomes fairly when a cell divides. Defective centromeres may underlie many cancers, in which problems with chromosome movement at cell division are common.
HELEN PEARSON | Nature News Service
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