Mitosis in human embryonic stem (hES) cell cytoplast cybrid following fusion. A, B, C, D: Increasing appearance in background of red fluorescence [octamer binding transcription factor-4 (Oct-4)] surrounded by ring of green fluorescence [tumour rejection antigen-2-39 (TRA-2-39)], with no nucleoli being present. Blue fluorescence: DAPI, showing the chromosome location. Original magnification x40.
Immune rejection problems could affect any one of us. This unique research shows that producing individual patient cell lines for our own future needs is now something we might all want to consider.
Somatic cell nuclear transfer (SCNT) forms the basis for obtaining patient specific stem cells and with the presence of reprogramming factors in human embryonic stem (hES) cells, a method for replacing the nuclei of hES cells by somatic cell nuclei has been widely sought.
Nick Strelchenko et al. based at the Reproductive Genetics Institute in Chicago, USA, has now developed an original technique resulting in the first evidence of the complete replacement of the nuclei of hES cells by nuclei of somatic cells. Their paper Reprogramming of human somatic cells by embryonic stem cell cytoplast is accepted and was published online by Reproductive BioMedicine Online, www.rbmonline.com/Article/2071 on 18 November 2005. The final article will also be published in print in the January 2006 issue of the journal.
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In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
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