Researchers at the Albert Einstein College of Medicine and the German Cancer Research Institute have shown how protein synthesis is targeted to certain regions of a cell--a process crucial for the cellular motility that governs nerve growth, wound healing and cancer metastasis. Their study appears in the November 24 issue of the journal Nature.
Led by Drs. Robert Singer and Dr Stefan Huettelmaier, the research team focused on migrating fibroblast cells important in wound healing. To move towards a wound, these cells manufacture the protein actin, which polymerizes into long filaments that push the cells membrane outward to form protrusions.
The teams previous work showed how newly formed actin messenger RNA molecules find their way to the cells periphery: A protein called ZBP1 binds to the messenger RNA and "escorts" it out of the fibroblast nucleus and into the cytoplasm. On reaching the cells periphery, the messenger RNA is translated into actin protein responsible for cell motility.
Karen Gardner | EurekAlert!
Synthetic nanoparticles achieve the complexity of protein molecules
24.01.2017 | Carnegie Mellon University
Immune Defense Without Collateral Damage
24.01.2017 | Universität Basel
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
24.01.2017 | Earth Sciences
24.01.2017 | Life Sciences
24.01.2017 | Physics and Astronomy