Provides new strategy for designing better treatments
Mayo Clinic researchers, working with colleagues at the University of Minnesota and University of Pittsburgh, are the first to describe a new role for a specialized cell of the immune system in children suffering from a rare muscle-damaging disease known as juvenile dermatomyositis (JDM). The specialized cells, called dendritic cells, have never before been found inside muscle tissue of JDM patients -- a discovery that suggests they are tightly linked to initiation of the disease process. The finding opens new possibilities for designing better treatments for JDM, and possibly for other related diseases such as multiple sclerosis, rheumatoid arthritis and lupus.
The Mayo Clinic-led research team report will be presented Nov. 14 as part of the American College of Rheumatology’s annual meeting in San Diego, Calif., held Nov. 12-17.
Lisa Lucier | EurekAlert!
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