At the Institut Curie, two CNRS teams have just reported crucial information on the orientation of cells as they divide. The cell division axis determines not only the position of the daughter cells but also their contents and hence their fate. The researchers have shown that the orientation of division depends on focal adhesions of the cell with its surroundings. They have also identified a new molecule that controls the localization of cellular determinants of so-called asymmetric cell division, thus giving rise to two different cells.
These two studies published in the October and November 2005 issues of Nature Cell Biology shed new light on one of the essential mechanisms in the life of a cell whose deregulation may give rise to cancer.
Division is an essential stage in the life of all cells: it participates in the body’s growth, wound repair, combating infection and in cell turnover. Within our bodies at any given moment some 250,000 million cells are dividing, that is 250,000 million mother cells are in the process of forming 500 000 million daughter cells. As individuals, however, we observe no change. This is because each newly formed cell has a well determined location. The mother cell has a given place among other cells in a tissue and, to avoid perturbing this organization, the daughter cells it produces are also appropriately placed. This very precise positioning is indispensable in maintaining the shape of our tissues and organs. The constraints imposed by the environment influence the division and position of the daughter cells.
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The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
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Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
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