At the Institut Curie, two CNRS teams have just reported crucial information on the orientation of cells as they divide. The cell division axis determines not only the position of the daughter cells but also their contents and hence their fate. The researchers have shown that the orientation of division depends on focal adhesions of the cell with its surroundings. They have also identified a new molecule that controls the localization of cellular determinants of so-called asymmetric cell division, thus giving rise to two different cells.
These two studies published in the October and November 2005 issues of Nature Cell Biology shed new light on one of the essential mechanisms in the life of a cell whose deregulation may give rise to cancer.
Division is an essential stage in the life of all cells: it participates in the body’s growth, wound repair, combating infection and in cell turnover. Within our bodies at any given moment some 250,000 million cells are dividing, that is 250,000 million mother cells are in the process of forming 500 000 million daughter cells. As individuals, however, we observe no change. This is because each newly formed cell has a well determined location. The mother cell has a given place among other cells in a tissue and, to avoid perturbing this organization, the daughter cells it produces are also appropriately placed. This very precise positioning is indispensable in maintaining the shape of our tissues and organs. The constraints imposed by the environment influence the division and position of the daughter cells.
Meadows beat out shrubs when it comes to storing carbon
23.11.2017 | Norwegian University of Science and Technology
Migrating Cells: Folds in the cell membrane supply material for necessary blebs
23.11.2017 | Westfälische Wilhelms-Universität Münster
Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
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