Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Link between maternal malaria, pregnancy history, and infant risk

08.11.2005


Every year at least 30 million women in malaria-endemic areas of Africa become pregnant. Many of them develop placental malaria, a pregnancy-specific form of the disease, which frequently results in low birth weight of the child. Placental malaria might increase the susceptibility of infants to malaria, but previous studies were inconclusive. A careful study by Patrick Duffy and colleagues (of the Seattle Biomedical Institute), published in the international open-access medical journal PLoS Medicine, found that placental malaria does raise the risk of malaria in infants. The researchers also discovered a surprising protective effect against malaria in first-time mothers, regardless of whether they had placental malaria.



Duffy and colleagues studied a total of 453 infants, of which 69 were born to mothers with placental malaria. Of those 69, 31 were born to first-time mothers, and 38 to mothers who had given birth before. They then followed those infants for a year and checked whether during that time they became sick with malaria. There were two major findings. First, the researchers found that overall children whose mothers had placental malaria were more likely to get sick with the disease themselves. Second, they found something surprising about the birth order of the infants, namely that children from first time mothers were less likely to develop malaria, regardless of whether their mother had placental malaria.

These results suggest that both the number of previous pregnancies and placental malaria affect an infant’s chances of developing malaria. It might be that in first-time mothers placental malaria stimulates the mother’s immune system and this somehow protects the baby against malaria. These provocative results will prompt further studies of the effects of malaria during pregnancy. If confirmed, the results here suggest that reducing placental malaria specifically in women who had previously given birth would have the most effect.

Paul Ocampo | EurekAlert!
Further information:
http://www.plos.org
http://www.plosmedicine.org

More articles from Life Sciences:

nachricht A novel socio-ecological approach helps identifying suitable wolf habitats
17.02.2017 | Universität Zürich

nachricht New, ultra-flexible probes form reliable, scar-free integration with the brain
16.02.2017 | University of Texas at Austin

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Biocompatible 3-D tracking system has potential to improve robot-assisted surgery

17.02.2017 | Medical Engineering

Real-time MRI analysis powered by supercomputers

17.02.2017 | Medical Engineering

Antibiotic effective against drug-resistant bacteria in pediatric skin infections

17.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>