While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution: different species make use of similar sets of proteins in different ways.
"Weve observed that organisms may share many similar proteins and yet retain very little parallel function among them," said Taylor Sittler, a medical student at the University of Massachusetts Medical School in Worcester, Massachusetts. "For instance, Plasmodium falciparum--the parasite that causes malaria--shares with its human host many proteins involved in forming chromosomes during cell division, but those proteins may interact in different ways, creating different cellular pathways and even entirely different functions. This contradicts the currently accepted paradigm that shared proteins interact simply because their genes are conserved. It was quite unexpected," he added.
Malaria is the third leading cause of infectious disease death in the world, after tuberculosis and AIDS. The World Health Organization estimates the parasite causes acute illness in some 300 million people each year, resulting in about 2.7 million deaths.
Jennifer Donovan | EurekAlert!
Warming ponds could accelerate climate change
21.02.2017 | University of Exeter
An alternative to opioids? Compound from marine snail is potent pain reliever
21.02.2017 | University of Utah
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
21.02.2017 | Earth Sciences
21.02.2017 | Medical Engineering
21.02.2017 | Trade Fair News