Alcohol, like any other substance that reinforces behaviour, such as another drug of abuse or even food, has a certain capacity to enhance social memory, that is, the ability to remember other individuals. If a mouse is administered alcohol immediately after being introduced to another animal of its own kind, the former will recognise the latter sooner. This phenomenon, which has significant implications when it comes to understanding the process underlying alcohol addiction, does not have a definitive explanation. However, a team of researchers from the Psychobiology Department at the University Jaume I (Spain) has revealed a part of the mystery, since they have proved that the substance responsible for enhancing social memory is not ethanol, but another compound derived from alcohol metabolism in the brain, namely, acetaldehyde.
The UJI team, headed by Psychobiology Professor Carlos González Aragón, has been working for years conducting experiments to prove that alcohol is metabolised not only in the liver but also in certain areas of the brain where important amounts of ethanol are processed through the action of an enzyme known as catalase. The substance derived from these reactions, acetaldehyde, is involved in many of the changes of behaviour typically associated to alcohol. Catalase metabolises alcohol in the brain and gives rise to a certain amount of acetaldehyde that, according to the researchers, would be responsible for the effects attributed to ethanol. If substances that enhance the action of catalase are administered, a higher production of acetaldehyde and a boost in its effects are observed, while acetaldehyde and most of the effects of ethanol are not produced when catalase inhibitors are used after having consumed a certain amount of alcohol.
Up to now, however, researchers had proved that brain catalase was involved in the stimulating effect of ethanol, but its role in complex cognitive processes such as learning and memory had not been dealt with. The work that we are now bringing to light, and which is the main point in the thesis of researcher Héctor Marín, proves this involvement. By administering catalase enhancers and inhibitors to mice, Marín has shown how the enzyme intervenes in the reinforcement of social memory.
Hugo Cerdà | alfa
Researchers develop eco-friendly, 4-in-1 catalyst
25.04.2017 | Brown University
Transfecting cells gently – the LZH presents a GNOME prototype at the Labvolution 2017
25.04.2017 | Laser Zentrum Hannover e.V.
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
25.04.2017 | Physics and Astronomy
25.04.2017 | Materials Sciences
25.04.2017 | Life Sciences