Pediatric surgeon looks to fetal cells to repair birth defects
Researchers at Children’s Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.
The tracheal repair technique is one of several tissue-engineering approaches pioneered at Children’s that use the fetus’s own cells, drawn from the amniotic fluid that surrounds it, to create patches to fix birth defects -- in this case, even before birth. Pediatric surgeon Dario Fauza, MD, who led the study, will present the team’s work on OOctober 8 at the American Academy of Pediatrics annual conference in Washington, DC.
Mary-Ellen Shay | EurekAlert!
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