Ensemble of usual sugars offers clues to controlling inflammation
A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohns disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.
Professor Hudson Freeze, Ph.D., director of Burnhams glycobiology and carbohydrate chemistry program, together with staff scientist Geetha Srikrishna, Ph.D., and other colleagues found that a naturally "tweaked" sugar chain normally present on white blood cells and intestinal cells plays a role in inflammation. In addition, the team found that an antibody produced in reaction to the sugars presence curbed intestinal inflammation induced in mice. These findings will be published in the October 15th edition of Journal of Immunology.
Nancy Beddingfield | EurekAlert!
The “Holy Grail” of peptide chemistry: Making peptide active agents available orally
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First line of defence against influenza further decoded
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For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
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Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
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Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
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Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
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