Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones. This is one of intriguing scientific results that emerge from the Second European Vascular Genomics Network Conference (EVGN Conference - Hamburg, September 27th - 30th 2005). These results provide new insights into the role of inflammation in heart disease and led to development of new informative models of blood clot formation and the processes that lead to heart attacks.
The inflammatory process is a sort of alarm bell that indicates the onset of atherosclerosis. In the recent past it had become clear that both innate and acquired immune responses mediated by white blood cells (inflammation) play a critical role in the development of this pathology. By altering tissue homeostasis (i.e. the whole of the metabolic events that maintain internal equilibrium) the inflammatory process paves the way towards the deposition of early fatty streaks. This event in turn stimulates endothelial activation (the endothelium is the inner lining of blood vessels) favouring the recruitment of infiltrating blood cells.
But what seemed quite a chaotic process turned out to be more organized than previously envisaged. Recently, Alain Tedgui, EVGN scientific coordinator (INSERM (Institut National de la Santé et de la Recherche Médicale, Paris, France) and colleagues have provided evidence that the immuno-inflammatory responses are tightly modulated: among the actors there are two anti-inflammatory cytokines that counter-balance the effects of other pro-inflammatory mediators.
Study shines light on brain cells that coordinate movement
26.06.2017 | University of Washington Health Sciences/UW Medicine
New insight into a central biological dogma on ion transport
26.06.2017 | Aarhus University
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...
19.06.2017 | Event News
13.06.2017 | Event News
13.06.2017 | Event News
26.06.2017 | Life Sciences
26.06.2017 | Physics and Astronomy
26.06.2017 | Information Technology