A new family of genes could hold the key to winning the battle against breast cancer, according to new research at the University of East Anglia.
Cancer specialists at UEA have discovered that several ‘ADAMTS’ genes are turned off in breast cancer compared to normal breast tissue, while others are switched on. These genes could be targets for the development of ‘smart’ drugs tailored to treat individual patients’ tumours.
The ADAMTS genes are recent additions to a large family known as the metalloproteinases – many of which can break down tissues and have therefore been linked with tumour metastasis, or spread, through the body. However, the ADAMTS group had not previously been linked to the development of breast cancer. These new findings suggest they could become robust ‘markers’, predicting disease outcome in breast cancer patients and identifying those patients most at risk of recurrence of the disease.
Simon Dunford | alfa
22.02.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau
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