As anyone whose nerves have been jangled by a babys howl or who have been riveted by the sight of an attractive person knows, nature has evolved sensory systems to be exquisitely tuned to relevant input. A major question in neurobiology is how neurons tune the strength of their interconnections to optimally respond to such inputs.
Neuronal circuitry consists of a web of neurons, each triggering others by launching bursts of neurotransmitters at targets on receiving neurons to produce nerve impulses in those targets. Neurons adjust the strength of those connections adaptively, to amplify or suppress connections. Some four decades ago, a general principle called the "efficient coding hypothesis" was formulated, holding that sensory systems adjust to efficiently represent the complex, dynamic sounds, sights, and other sensory input from the environment.
Writing in the August 4, 2005, issue of Neuron, researchers led by Christian K. Machens of Cold Spring Harbor Laboratory and Andreas Herz of Humboldt-University Berlin describe experiments with grasshopper auditory neurons that reveal new details of such sensory coding. Their findings show that "optimal stimulus ensembles" that trigger the neurons differ from those the grasshopper hears in the natural environment but largely overlap with components of natural sounds found in mating and mate-location calls.
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21.09.2017 | Christian-Albrechts-Universität zu Kiel
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21.09.2017 | NIH/National Institute of Neurological Disorders and Stroke
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
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