This week scientists of the Flanders Interuniversity Institute for Biotechnology (VIB) will once again publish a breakthrough in their research regarding Alzheimer’s disease. The researchers, this time connected to the Catholic University of Leuven, discovered the function of one of the most important proteins related to Alzheimer’s disease. They have indicated that the protein stimulates the growth of nerve paths in the brain, which is essential for recovery after brain damage. The results are published in the authoritative journal EMBO Journal.
The normal function of the amyloidal precursor protein or APP clarified
It has been known for several years that APP is relevant in Alzheimer’s disease. APP is the precursor of the amyloidal-ß protein that causes the typical ‘plaques’ in the brains of patients. The normal function of APP was, however, not known. Maarten Leyssen and his colleagues have indicated that APP stimulates the development of nerve paths. Intact nerve paths are essential for the proper functioning of the brain. These connections can be damaged after traumatic brain damage resulting in the improper functioning of the brain. APP is responsible for stimulating the development of new nerve paths.
Ann Van Gysel | alfa
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