Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Killer into cure – using viruses to treat cancer

01.08.2005


The natural ability of viruses to infect and destroy cells is being used by scientists to kill cancerous tumours, according to an article in the August 2005 issue of Microbiology Today, the quarterly magazine of the Society for General Microbiology.



Professor Moira Brown of Southern General Hospital in Glasgow explains how viruses that cause common diseases, such as cold sores and ‘flu, have been modified so that they are no longer harmful, but can target and kill only cancerous cells.

Safety trials have been completed for some of these cancer-killing viruses and now new trials are underway to test how effective they are.


“If we can demonstrate the effectiveness of the viruses, the potential is there to transform the future for people who have cancers that are otherwise untreatable,” said Professor Brown.

“Viruses are normally thought of as ‘bad guys’, but our knowledge and understanding of how they function and how cells become cancerous has allowed them to be turned into ‘good guys’,” said Professor Brown. “These basic laboratory findings have been transferred to the clinic to control a killer disease.”

One of the viruses, HSV1716, has been given approval by the European Medicines Agency and the UK Department of Health for a crucial efficacy trial in patients with glioma, a type of brain tumour. This will be the most advanced trial of its type and should determine the effectiveness of the therapy.

Cancer is a major killer, affecting around one in three people in Western societies. This issue of Microbiology Today focuses on the many relationships between cancer and microbes.

Other features in the August 2005 issue of Microbiology Today include:
· An introduction to viruses and cancer (page 110)
· Bacteria in cancer therapy (page 113)
· Human papillomaviruses and cancer (page 116)
· Nobel microbes define the art of cell division (page 122)
· Comment: a microbiologist’s view of astrobiology (page 156)

These are just some of the articles that appear, together with all the regular features and reports of Society activities.

Faye Jones | alfa
Further information:
http://www.sgm.ac.uk

More articles from Life Sciences:

nachricht Nanoparticle Exposure Can Awaken Dormant Viruses in the Lungs
16.01.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Cholera bacteria infect more effectively with a simple twist of shape
13.01.2017 | Princeton University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Multiregional brain on a chip

16.01.2017 | Power and Electrical Engineering

New technology enables 5-D imaging in live animals, humans

16.01.2017 | Information Technology

Researchers develop environmentally friendly soy air filter

16.01.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>