A specialized subpopulation of the antibody-producing B cells of the immune system plays a "double-barreled" role in triggering both kinds of immunity -- innate and acquired, Duke University Medical Center immunologists have discovered. The division of labor between B-1a and B-1b cells they have uncovered offers basic insights that could contribute to more rational development of vaccines, they said.
B cells are the arms factories of the immune system, producing antibodies that target invading microbes for destruction. Generally, B-1 cells have been thought to play a major role in the innate immune response -- the type of immunity that offers rapid, generalized responses to infections. Less understood has been any role in adaptive immunity -- in which the immune system develops a long-term immune response to an invader after vaccination or infection.
The researchers -- Karen Haas, Jonathan Poe, Douglas Steeber and Thomas Tedder -- published their findings in the July 2005 issue of the journal Immunity. The research was sponsored by the National Institutes of Health, the Arthritis Foundation, the Lymphoma Research Foundation and the Leukemia & Lymphoma Society.
Dennis Meredith | EurekAlert!
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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