Scientists at The University of Nottingham have announced an important biological breakthrough that could offer new hope in the fight against liver cancer.
Professor John Mayer and Dr Simon Dawson, in collaboration with colleagues at Japan’s Kyoto University, have discovered the function of a new liver oncoprotein — or cancer causing protein — which could be the first step to finding effective new treatments for the deadly illness.
The research, published today in the journal Cancer Cell, centres on the most common malignant liver cancers, hepatocellular carcinomas, which arise from the liver cells themselves. Primary liver cancer is relatively rare in the UK and other countries in the Western world, but is very common in Africa and Asia — it is strongly associated with hepatitis virus infection and with a natural toxin called aflatoxin which is present in mouldy peanuts, soybeans, groundnut, corn and rice. There is currently no cure for primary liver cancer and survival rates are low.
Professor John Mayer | alfa
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