As a part of a research collaboration, scientists at the Sahlgrenska Academy at Göteborg University, Sweden, have developed a new drug candidate against HIV-infection. The new substance, named alphaHGA, will be tested on patients this year. In a thesis from the Sahlgrenska Academy, parts of the research essential for the performance of the clinical trial are presented.
At the end of 2004, approximately 40 million people were living with HIV-infection, most of them in southern Africa. Annually, approximately three million people die from the infection, many of them young. Despite huge efforts, there has been no success in developing a vaccine against HIV. However, a number of drugs are used for treatment of HIV-infected individuals. The drugs cannot cure an infected person, but can slow down the disease progression. There are about 20 drugs commercially available, but since the virus can develop resistance and since the drugs are associated with side effects, there is a need for new, safer drugs.
Elin Andersson, M.Sc, presents in her thesis studies showing that the compound GPG-NH2 inhibits HIV in culture.
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Oestrogen regulates pathological changes of bones via bone lining cells
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Programming cells with computer-like logic
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Spectrally narrow x-ray pulses may be “sharpened” by purely mechanical means. This sounds surprisingly, but a team of theoretical and experimental physicists developed and realized such a method. It is based on fast motions, precisely synchronized with the pulses, of a target interacting with the x-ray light. Thereby, photons are redistributed within the x-ray pulse to the desired spectral region.
A team of theoretical physicists from the MPI for Nuclear Physics (MPIK) in Heidelberg has developed a novel method to intensify the spectrally broad x-ray...
Physicists working with researcher Oriol Romero-Isart devised a new simple scheme to theoretically generate arbitrarily short and focused electromagnetic fields. This new tool could be used for precise sensing and in microscopy.
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Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers
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Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.
At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
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