A 3-D model of a DNA nanostructure. In figure A, three long cylinders of individual helices (black) contain regularly spaced intervals of aptamers (red) which can bind to a protein. In figure (B), a thrombin protein (green circle) binds to the DNA aptamer structure.
An atomic force microscopy image of the thrombin/DNA complex. The DNA appears as two long threads in the center of the image, with the brighter spots corresponding to thrombin proteins attached to the DNA.
In the fifty-year history since the structure of DNA was first revealed, what was once a Nobel prize- winning research discovery has become an omnipresent cultural icon co-opted for promoting everything from fragrances to musical acts. Now, the familiar DNA double helix is serving as a microscopic trellis in order to further advances in nanotechnology aimed at improving human health.
Hao Yan, a researcher at the Biodesign Institute at Arizona State University and an assistant professor in ASU’s Department of Chemistry and Biochemistry, recently created unique arrays of proteins tethered onto self-assembled DNA nanostructures.
While other efforts in recent years have focused on learning how to build DNA-based nanostructures, Yan’s work is novel because it makes it feasible to attach any desired biomolecule onto DNA nanostructures. Such work is an important step and can serve as a future foundation for biocatalytic networks, drug discovery or ultrasensitive detection systems.
Making fuel out of thick air
08.12.2017 | DOE/Argonne National Laboratory
‘Spying’ on the hidden geometry of complex networks through machine intelligence
08.12.2017 | Technische Universität Dresden
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications
Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
Physicists in the Laboratory for Attosecond Physics (run jointly by LMU Munich and the Max Planck Institute for Quantum Optics) have developed an attosecond electron microscope that allows them to visualize the dispersion of light in time and space, and observe the motions of electrons in atoms.
The most basic of all physical interactions in nature is that between light and matter. This interaction takes place in attosecond times (i.e. billionths of a...
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