Physicians have won the victory over the natural variola virus: it does not exist in nature any longer. Now, it is also necessary to destroy the viruses kept in the laboratory, however, their genetic material should be preserved. Resolution of this task in Russia is funded by the International Science and Technology Center (ISTC).
Specialists of the State Research Center of Virology and Biotechnology “Vector” (Ministry of Health of the Russian Federation) supported by the International Science and Technology Center (ISTC) disassembled into fragments complete genomes of 8 cultures of natural variola viruses. In such a form, virus’ genome can be kept for a very long time and used for research work without fear that the virus itself will get into disposal of terrorists or will “escape” the laboratory as a result of an accident.
Large-scale actions undertaken by the world community under the aegis of the World Health Organization allowed to fully eliminate natural variola. At present, natural variola viruses are preserved only in collections of two collaborative research centers: in the Center for Disease Control and Prevention (CDC) (Atlanta, USA) and in the State Research Center of Virology and Biotechnology “Vector”. Since 1980, immunization of population against natural variola virus was ceased in all countries, and the amount of people sensitive to this disease is constantly growing. Repositories of viable cultures of the virus are a source of possible biological hazard. Therefore, World Health Organization decided in 1986 that it was necessary to destroy all collections of natural variola virus’ cultures and their DNAs. Extermination is inevitable, but it will be a great loss for virology and medicine. Firstly, functioning and organization of this virus have not been studied in detail, secondly, although nobody falls ill with natural variola now, specialists should have the opportunity to develop contemporary express-diagnostics methods. To continue the research, the Russian scientists had to develop a safe way for preservation of genetic material of this virus.
Sergey Komarov | alfa
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