Gene for lung and diaphragm development in mice and humans
To breathe normally, people need more than just healthy lungs. A diaphragm—the large muscle that creates a vacuum to draw air into their lungs—is also crucial. Birth defects in the diaphragm, such as congenital diaphragmatic hernia (which are about as common as cystic fibrosis), are often fatal. “A lot of people haven’t heard of this [disorder] because so many of the kids die early,” said Kate Ackerman, Harvard Medical School researcher and lead author of the study in PLoS Genetics.
To explore the genetic roots of these birth defects—hitherto a mystery—Ackerman and her colleagues screened mice with induced genetic mutations. The researchers discovered that a mutation in the mouse Fog2 gene can cause small lungs and abnormal diaphragm development. Could the same gene be involved in human diaphragmatic defects? After studying children with similar problems, the authors did indeed identify a child with a serious Fog2 gene mutation who died on the first day of life with severe breathing difficulties, small lungs, and an abnormal diaphragm.
Paul Ocampo | alfa
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University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
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20.10.2017 | Interdisciplinary Research