Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

How cell suicide protects plants from infection

13.06.2005


A protective zone of dead cells (brown) around a virus invasion (purple) halts the spread of virus. Credit: Nicolle Rager Fuller, NSF


Researchers at Yale have identified a gene that regulates the major immune response in plants, programmed cell death (PCD), according to a recent report in the journal Cell.

To protect themselves from viruses, plants create a zone of dead cells around an infection site that prevents the infection from spreading. Savithramma Dinesh-Kumar, associate professor of Molecular, Cellular and Developmental Biology at Yale and his colleagues discovered how the plants keep from killing themselves after they turn on the cell-suicide PCD process.

Dinesh-Kumar first developed a technique for silencing or inactivating plant genes -- a technique that is now used by several research groups. His group studies the interaction between plants and viruses using tobacco as a model system.



They identified and silenced a "pro-survival" gene, BECLIN-1, that is important in the PCD response. When BECLIN-1 is active, infection is localized to a small number of cells that later die and form discrete brown lesions on the leaves. When the gene is inactivated, the plant can no longer regulate PCD, leading to cell death throughout the leaf and plant.

PCD has been described in virtually all cell types, both plant and animal. It is an important aspect of many biological processes including immune system function, embryonic development and elimination of defective cells. Failure of PCD can result in devastating diseases such as cancer, Alzheimer’s and AIDS.

"This work gives us a better understanding of how plants fend off microbial attacks through carefully controlled destruction of infected cells," said James Anderson, of the Division of Genetics and Developmental Biology at the National Institute of General Medical Sciences (NIGMS). "Like other studies carried out in model organisms, these findings shed light on similar processes that occur in mammals, and may eventually be used to better human health."

Janet Rettig Emanuel | EurekAlert!
Further information:
http://www.yale.edu

More articles from Life Sciences:

nachricht At last, butterflies get a bigger, better evolutionary tree
16.02.2018 | Florida Museum of Natural History

nachricht New treatment strategies for chronic kidney disease from the animal kingdom
16.02.2018 | Veterinärmedizinische Universität Wien

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

Im Focus: Autonomous 3D scanner supports individual manufacturing processes

Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).

Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Fingerprints of quantum entanglement

16.02.2018 | Information Technology

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers

16.02.2018 | Health and Medicine

Hubble sees Neptune's mysterious shrinking storm

16.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>