Collaborative effort develops novel tool and discovers surprising correlation of microRNA expression and cancer type
Despite significant progress in understanding the genetic changes in many different cancers, diagnosis and classification of tumor type remain, at best, an imperfect art. This could change quickly, thanks to the findings of a group of researchers from the Broad Institute of MIT and Harvard, the Dana-Farber Cancer Institute, MIT, and St. Judes Childrens Research Hospital in Memphis, TN.
In the June 9 issue of Nature, the scientists describe two important breakthroughs: (1) a surprisingly accurate correlation of the 217 known human microRNAs (miRNAs – small noncoding RNA molecules that control the levels of proteins made from transcribed genes) with the development and differentation of tumors, and (2) the development of a technology that not only enabled this exciting discovery but that could be the basis for an easy and inexpensive diagnostic test.
Michelle Nhuch | EurekAlert!
One step closer to reality
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University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
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20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy