Plasso Technology Ltd has been awarded a Small Business Research Initiative (SBRI) grant by the Biotechnology and Biological Sciences Research Council (BBSRC) to develop a sugar array.
Plasso provides novel solutions for the immobilisation and presentation of biomolecules for use in a range of biological assays. One class of biological molecule that has proven particularly difficult to immobilise in this regard is glycosaminoglycans, (GAGs). GAGs are found on the surface of all cells and are important in mediating cell-cell and cell-protein interactions; they are implicated in the progression of many diseases, such as cancer, DVT, arthritis. The ability to study these molecules using modern molecular techniques such as arrays and biochips requires that they can be immobilised whilst retaining their functionality.
This SBRI support will lead to the development of proto-type GAG arrays. Such arrays would have a myriad of potential uses including the screening of potential drug candidates, as well as providing an important tool for researchers, exploring specific biochemical pathways.
Sameer Kothari | alfa
Flow of cerebrospinal fluid regulates neural stem cell division
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The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
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Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
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A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
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