An international research team has discovered a new target molecule, Fbw7, for developing drugs with the potential to complement or replace statins in the treatment of cardiovascular diseases. The findings are being published in the new issue of the scientific journal Cell Metabolism.
Cholesterol is a fat-like substance that is needed for the formation of our cells and for the production of hormones. The amount needed can be provided by the body itself, but our eating habits often lead to too much cholesterol. The surplus is stored in the walls of our vessels, thereby increasing the risk of cardiovascular disorders, the most common cause of death in the Western world. What‚s more, individuals with cardiovascular diseases run a greater risk of being overweight and contracting diabetes.
The protein SREBP regulates the genes that control the amount of cholesterol and other fats in cells. SREBP‚s ability to regulate the new production, metabolism, and uptake of cholesterol from the blood is extremely important in the liver, where huge quantities of cholesterol are absorbed and rendered harmless. SREBP is therefore a suitable target molecule for the development of new drugs for cardiovascular diseases, overweight, and diabetes.
Anneli Waara | alfa
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory
Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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