Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bacterium manipulates the human defence system: The Borrelia bacterium is a master of disguise

20.05.2005


Borrelia bacteria are capable of masking themselves in the human body and deceiving the immune defence system. In this way they can hide in the human organism even for periods of years. In their recent studies Professor Seppo Meri and his team have managed to trace the evasive movements of the Borrelia bacterium in the body. Their work is part of the Microbes and Man research programme, jointly funded by the Academy of Finland and the Swedish Foundation for Strategic Research.



When they first enter the human organism, Borrelia bacteria do not always cause very intense inflammation. However, they proliferate unnoticed and later on the symptoms get worse. The immune system is unable in this situation to respond because the bacterium actively prevents any defensive reactions.

Professor Meri and his team have found that Borrelia bacteria, which are carried by ticks and birds, are capable of absorbing the protein that controls human inflammation (complement factor H). Normally, antibodies and the complement would kill off the bacteria, but this ingenious kidnap operation allows the Borrelia bacteria to disguise themselves and avoid being killed or devoured by inflammation cells. Consequently, the bacteria can continue to proliferate in the body and even reach the brain. An advanced bacterium may lead to a serious condition known as neuroborreliosis, which among other things may cause chronic headache or facial nerve paralysis.


One of the difficulties in diagnosing the symptoms caused by the Borrelia bacterium is that only half of all people who get a tick bite develop the tell-tale rash. Therefore, the bacterium often gets to make its way into the body and eventually into the bloodstream through the skin. Some one in ten patients are unable to shake off their symptoms even if they receive proper antibiotic treatment.

Tiina Pohjois-Koivisto | alfa
Further information:
http://www.aka.fi

More articles from Life Sciences:

nachricht Complete skin regeneration system of fish unraveled
24.04.2018 | Tokyo Institute of Technology

nachricht Scientists generate an atlas of the human genome using stem cells
24.04.2018 | The Hebrew University of Jerusalem

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: BAM@Hannover Messe: innovative 3D printing method for space flight

At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.

Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...

Im Focus: Molecules Brilliantly Illuminated

Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.

Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...

Im Focus: Spider silk key to new bone-fixing composite

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Complete skin regeneration system of fish unraveled

24.04.2018 | Life Sciences

Scientists create innovative new 'green' concrete using graphene

24.04.2018 | Materials Sciences

BAM@Hannover Messe: innovative 3D printing method for space flight

24.04.2018 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>