Turns out building cars and building life have a lot in common – it all comes down to quality control.
Scientists at Michigan State University have made a major discovery on the inner workings of genetic coding, mapping out mechanisms of one of lifes most elemental functions: RNA synthesis. Their work has crucial implications for how a normal cell forms a tumor and how a virus runs amok. The work is published in the May 13 edition of the scientific journal Molecular Cell.
Behind the basic research is a story that melds exquisite nanotechnology in living systems and cutting-edge biochemistry and molecular biology with a system of checks and balances. "RNA synthesis is at the hub of human genetic control. Its important for understanding cancers, viral infections and normal human development," said Zachary Burton, professor of biochemistry and molecular biology. "If you want to understand and control things like viral infections and tumors this fundamental process has to be understood in every detail. This is basic science, but basic science with practical application."
Zachary Burton | EurekAlert!
Signaling Pathways to the Nucleus
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For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
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