UCLA Neuropsychiatric Institute study reveals new approach
Scientific theory holds that Huntingtons disease (HD) is caused by a mutant protein that arises within brain cells and kills them, triggering the genetic neurological disorder. Now a new UCLA Neuropsychiatric Institute study reveals the first strong evidence that the mutant protein also elicits toxic interactions from neighboring cells to provoke the fatal brain disorder. The May 5 edition of Neuron reports the findings.
"This is really important because most current disease models and drug development efforts rely on the assumption that Huntingtons disease arises from within the target brain cells," explained Dr. William Yang, assistant professor at the UCLA Neuropsychiatric Institute and a member of the Brain Research Institute.
Elaine Schmidt | EurekAlert!
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