In a paper in this months freely-available online global health journal PLoS Medicine Seung Kim and colleagues from Stanford University suggest that one way of producing insulin-secreting pancreatic islet cells for future possible treatment of type I diabetes is to look beyond immature pancreatic cells and embryonic stem cells to other early cell types. Kim and colleagues took cells derived from brain which usually mature into neural cells, and exposed them to a series of signals that are known to drive pancreatic islet development. They were able to produce clusters of insulin-producing cells that responded to glucose out of the body.
Insulin-producing neurospheres. (Photo: Seung Kim et al.)
When the cells were then transplanted into immunocompromised mice the cells could also be stimulated by glucose to produce human insulin. Future work will need to establish the long-term stability and safety of these cells and to work out how to scale up such a process to produce the much larger numbers of cells that would be needed for human treatment. However, the authors conclude that this technique "could serve as the basis for developing replacement islets from a wide range of human stem cells, including neural stem cells and ES cells."
Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München
Second research flight into zero gravity
21.10.2016 | Universität Zürich
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
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21.10.2016 | Materials Sciences