A team of researchers at the Universitat Autònoma de Barcelona has developed new miniature sensors for analysing DNA. The sensors have the same size and thickness as a fingernail and reduce the time needed to identify DNA chains to several minutes or a few hours, depending on each chain. These sensors can be applied to many different tasks, ranging from paternity tests and identifying people to detecting genetically modified food, identifying bacterial strains in foodborne illnesses and testing genetic toxicity in new drugs. Once mass production of the sensors begins, their cost and availability will be similar to that of pregnancy test kits found in pharmacies.
The researchers Salvador Alegret, Manuel del Valle and Maria Isabel Pividori, all of whom are members of the Sensors and Biosensors Group at the UAB’s Department of Chemistry, developed the new sensors based on their experience in research with electrochemical sensors. These can identify a substance by chemically interacting with it and converting this interaction into an electrical current that they measure.
To detect DNA, the new miniaturised electrochemical genosensors have a probe containing DNA fragments that complement the DNA they aim to detect. For example, to detect Salmonella in a sample of mayonnaise, the probe has fragments of the type of DNA that complements that found in a group of genes that identify the bacteria. When the probe is submerged into the mayonnaise, some of the DNA fragments from the bacterial cells join the complementing fragments from the probe, creating a measurable electrical current. The sensor converts this current into a signal that can be seen by the person controlling the tests, making him aware there are bacteria. Also, because the sensors are very small and easy to manipulate, it is possible to assemble a set of sensors that can collect data simultaneously and deduce information about the bacteria such as which strain caused the foodborne illness.
Octavi López Coronado | alfa
Shrews shrink in winter and regrow in spring
24.10.2017 | Max-Planck-Institut für Ornithologie
'Y' a protein unicorn might matter in glaucoma
23.10.2017 | Georgia Institute of Technology
Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
24.10.2017 | Life Sciences
23.10.2017 | Life Sciences
23.10.2017 | Physics and Astronomy