Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Food preservative neutralizes anthrax spores

22.03.2005


Nisin, a commonly used food preservative effectively neutralizes anthrax spores and could be used to decontaminate skin in the event of exposure. Researchers from Biosynexus, Inccorporated report their findings today at the 2005 American Society for Microbiology Biodefense Research Meeting.



"Contamination of human skin with even a few spores may potentially disseminate disease beyond the initial area of attack," says John Kokai-Kun, a researcher on the study. "There is currently nothing specifically approved for decontaminating human skin of anthrax spores."

Nisin is a natural antimicrobial peptide used as a preservative in heat-processed and low pH foods. It is derived from the controlled fermentation of the naturally occurring milk bacteria Lactococcus lactis. Nisin was awarded the Generally Regarded as Safe (GRAS) designation in the U.S. Federal Register of April, 1988 and is approved as a natural food preservative in the United States. It is also being used in the dairy industry as a topical treatment for mastitis.


Kokai-Kun and his colleagues tested the ability of nisin to neutralize spores of both anthrax and a related microbe, Bacillus cereus. Spores were pre-treated with nisin and then given variety of tests, including their ability to germinate and to cause disease in mice. While untreated spores in a control group were able to germinate and grow in culture and cause lethal infection in mice, the treated spores remained dormant and caused no apparent disease.

The next step for the researchers is to formulate a delivery system. One that appears to have promise is an impregnated wipe. A similar product, with a much lower concentration of nisin than would be necessary against anthrax is already available commercially for treating mastitis in cows. Other options include a topical cream or a foam.

"Given the capacity of nisin to neutralize spores, its common topical use on animals and its GRAS status, we are developing nisin-based formulations for decontamination of human skin exposed to anthrax spores," says Kokai-Kun.

Jim Sliwa | EurekAlert!
Further information:
http://www.asmusa.org

More articles from Life Sciences:

nachricht First line of defence against influenza further decoded
21.02.2018 | Helmholtz-Zentrum für Infektionsforschung

nachricht Helping in spite of risk: Ants perform risk-averse sanitary care of infectious nest mates
21.02.2018 | Institute of Science and Technology Austria

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

MEMS chips get metatlenses

21.02.2018 | Physics and Astronomy

International team publishes roadmap to enhance radioresistance for space colonization

21.02.2018 | Physics and Astronomy

World's first solar fuels reactor for night passes test

21.02.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>