Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genes Against By-Product-Coking Industry

22.02.2005


How can workers be protected from detrimental production factors? Russian researchers have come to the conclusion that this can be done by a large number of actively working ribosomal genes.



Specialists of the Chair of Genetics, Kemerovo State University, have discovered that people with a large number of actively working ribosomal genes are found more frequently among workers of the by-product coke plant than among ordinary townsmen (ribosomal genes are responsible for the ribosome structure). According to the researchers, activity of ribosomal genes protects their possessors from detrimental production factors.

Listing detrimental factors of by-product coke plants is a long and tiresome effort. Multiple toxic and mutagenic chemical agents, noise, vibration and temperature difference are destructive for health.


Nevertheless, a lot of people have been working in such environment for more than 20 years and feeling well. What is the matter? It has turned out that the point is the number of actively working ribosomal genes. Human genome contains excess amount of these genes. “Redundant” genes simply do not work, the remaining ribosomal genes providing for normal vital activity of the cell and the organism. People differ in individual doses of working ribosomal genes, this difference being hereditary.

Ribosomal genes are placed compactly in certain sections of chromosomes. Upon special coloring by silver nitrate, the active genes zone is seen as a black spot. The larger and the brighter the spot is, the more working ribosomal genes are contained in it.

Genetics have examined several dozens of workers of different sex and age from the by-product coke plant – Kemerovo joint-stock company KOKS (“Coke”). Having produced chromosomal preparations from the cells of peripheral blood, genetics made sure that there are more people among workers of the plant with high dose of active genes than those among healthy donors who do not contact with occupational hazard.

Along with that, the workers whose record of service exceeds 10 years have larger amount of active copies of ribosomal genes than the background donors and workers with the record of service under 10 years.

The researchers suggest two hypotheses for explanation of this phenomenon. Firstly, inactive copies may be enabled after the lapse of many years of work in harmful conditions.

Secondly, mainly workers with initial large number of active copies can endure working at the plant for more than ten years, the others would simply leave. Apparently, higher activity of ribosomal genes helps their possessors to adapt to difficult conditions of the by-product-coking industry.

Indeed, such people are less sensitive to mutagens. The Kemerovo researchers have ascertained that the cells with higher level of chromosomal derangements are found less frequently with the workers possessing a large number of working ribosomal genes. According to the researchers’ opinion, there is dependence between genetic sensitivity to production factors and an individual dose of active ribosomal genes. Therefore, it is expedient to check activity of these genes with all applicants for job at the by-product coke plant.

Sergey Komarov | alfa
Further information:
http://www.informnauka.ru

More articles from Life Sciences:

nachricht Water world
20.11.2017 | Washington University in St. Louis

nachricht Carefully crafted light pulses control neuron activity
20.11.2017 | University of Illinois at Urbana-Champaign

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Antarctic landscape insights keep ice loss forecasts on the radar

20.11.2017 | Earth Sciences

Filling the gap: High-latitude volcanic eruptions also have global impact

20.11.2017 | Earth Sciences

Water world

20.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>