Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genes Against By-Product-Coking Industry

22.02.2005


How can workers be protected from detrimental production factors? Russian researchers have come to the conclusion that this can be done by a large number of actively working ribosomal genes.



Specialists of the Chair of Genetics, Kemerovo State University, have discovered that people with a large number of actively working ribosomal genes are found more frequently among workers of the by-product coke plant than among ordinary townsmen (ribosomal genes are responsible for the ribosome structure). According to the researchers, activity of ribosomal genes protects their possessors from detrimental production factors.

Listing detrimental factors of by-product coke plants is a long and tiresome effort. Multiple toxic and mutagenic chemical agents, noise, vibration and temperature difference are destructive for health.


Nevertheless, a lot of people have been working in such environment for more than 20 years and feeling well. What is the matter? It has turned out that the point is the number of actively working ribosomal genes. Human genome contains excess amount of these genes. “Redundant” genes simply do not work, the remaining ribosomal genes providing for normal vital activity of the cell and the organism. People differ in individual doses of working ribosomal genes, this difference being hereditary.

Ribosomal genes are placed compactly in certain sections of chromosomes. Upon special coloring by silver nitrate, the active genes zone is seen as a black spot. The larger and the brighter the spot is, the more working ribosomal genes are contained in it.

Genetics have examined several dozens of workers of different sex and age from the by-product coke plant – Kemerovo joint-stock company KOKS (“Coke”). Having produced chromosomal preparations from the cells of peripheral blood, genetics made sure that there are more people among workers of the plant with high dose of active genes than those among healthy donors who do not contact with occupational hazard.

Along with that, the workers whose record of service exceeds 10 years have larger amount of active copies of ribosomal genes than the background donors and workers with the record of service under 10 years.

The researchers suggest two hypotheses for explanation of this phenomenon. Firstly, inactive copies may be enabled after the lapse of many years of work in harmful conditions.

Secondly, mainly workers with initial large number of active copies can endure working at the plant for more than ten years, the others would simply leave. Apparently, higher activity of ribosomal genes helps their possessors to adapt to difficult conditions of the by-product-coking industry.

Indeed, such people are less sensitive to mutagens. The Kemerovo researchers have ascertained that the cells with higher level of chromosomal derangements are found less frequently with the workers possessing a large number of working ribosomal genes. According to the researchers’ opinion, there is dependence between genetic sensitivity to production factors and an individual dose of active ribosomal genes. Therefore, it is expedient to check activity of these genes with all applicants for job at the by-product coke plant.

Sergey Komarov | alfa
Further information:
http://www.informnauka.ru

More articles from Life Sciences:

nachricht Identified the component that allows a lethal bacteria to spread resistance to antibiotics
27.07.2017 | Institute for Research in Biomedicine (IRB Barcelona)

nachricht Seeing more with PET scans: New chemistry for medical imaging
27.07.2017 | DOE/Lawrence Berkeley National Laboratory

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Physicists Design Ultrafocused Pulses

Physicists working with researcher Oriol Romero-Isart devised a new simple scheme to theoretically generate arbitrarily short and focused electromagnetic fields. This new tool could be used for precise sensing and in microscopy.

Microwaves, heat radiation, light and X-radiation are examples for electromagnetic waves. Many applications require to focus the electromagnetic fields to...

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

 
Latest News

Physicists gain new insights into nanosystems with spherical confinement

27.07.2017 | Materials Sciences

Seeing more with PET scans: New chemistry for medical imaging

27.07.2017 | Life Sciences

Did you know that infrared heat and UV light contribute to the success of your barbecue?

27.07.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>