As the next phase of DTI’s Measurements for Biotechnology (MfB) programme to 2007 gets underway, a large DNA microarray dataset generated by an LGC-led consortium during the first phase is now freely available online at ArrayExpress, a leading public repository managed by the European Bioinformatics Institute (EBI). The sharing of well-annotated data is a primary objective of the Microarray Gene Expression Data (MGED) Society and this repository is stored in accordance with MGED recommendations.
Since the mid-1990s, DNA microarray technology has developed into a major tool for the investigation of global gene expression for all aspects of human disease. The technology is currently being explored for its efficacy in genomic approaches to toxicology. As toxicity is still the major cause of failure in clinical trials, there is strong industry interest in improved models for predictive toxicology.
Dr Carole Foy of LGC’s Bio-Molecular Innovation group said: "This dataset is a significant milestone from the MfB project, ‘Comparability of gene expression measurements,’ completed in 2004. It is a tribute to everyone involved in the consortium - NPL, Human Genome Mapping Project, Oxford Biomedica, Renovo and Royal London Hospital - that other scientists and analysts can now access this valuable data.
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Magnetic resonance imaging, or MRI, is a widely used medical tool for taking pictures of the insides of our body. One way to make MRI scans easier to read is...
At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.
Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...
Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.
Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
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