Charles Fisher, Penn State and Pat Hickey, Woods Hole Oceanographic Institution - Permission is granted for one-time use to illustrate articles about this research only.
This is an image of a group of the giant hydrothermal vent tubeworm, Riftia pachyptila, taken around 2500 m at 9ºN along the East Pacific Rise (Pacific Ocean). The red portion of the worm exposed at the top of the white tube is the gas exchange organ, or plume. This is where sulfide and oxygen enter the worm and bind to the hemoglobins. The plume gets its deep red color from the large extracelllular hemoglobins circulating throughout the worm.
The discovery that zinc contained in the hemoglobin of deep-sea tubeworms is used to bind and transport nutrients to symbiotic bacteria will be published online in the Proceedings of the National Academy of Science during the week of 14 February 2005. Further research with the hemoglobin could lead to its use in a variety of ways, including as an artificial substitute for oxygen carriers in human blood.
Tubeworms living near hydrothermal vents and cold seeps in the world’s oceans must adapt to sulfide levels that would prove lethal to most aquatic life while simultaneously providing hydrogen sulfide molecules to symbiotic bacteria within their bodies. A Penn State research team, in collaboration with researchers at the University of Massachusetts Medical School in Worcester and in the United Kingdom, reports a new mechanism for sulfide binding in the hemoglobins, the same molecules that carry oxygen to the worm’s own cells. The research team reports that zinc ions in the hemoglobin bind hydrogen sulfide, the first example of any hemoglobin incorporating a metal specifically for that purpose.
"The worms need to bind free sulfide so that it doesn’t react with oxygen, to reduce sulfide exposure in their tissues, and to provide the sulfide to the bacteria that, as far as we know, provide all of the worm’s nutritional needs," says Charles Fisher, professor of biology at Penn State, whose research team includes Penn State graduate assistant Jason Flores, the lead author of the research paper, and William Royer, professor of biochemistry and molecular pharmacology at the University of Massachusetts. "Our discovery, which results from a very multi-disciplinary approach, replaces the current paradigm for the evolution of worm hemoglobin by demonstrating that hydrogen-sulfide molecules are bound by a metal ion rather than by an arrangement of amino acids."
Barbara K. Kennedy | EurekAlert!
Complete skin regeneration system of fish unraveled
24.04.2018 | Tokyo Institute of Technology
Scientists generate an atlas of the human genome using stem cells
24.04.2018 | The Hebrew University of Jerusalem
At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.
Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...
Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.
Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
24.04.2018 | Life Sciences
24.04.2018 | Materials Sciences
24.04.2018 | Trade Fair News