Finnish researchers have discovered an interesting link between lactose malabsorption and the occurrence of bone fracture in elderly people.
It was three years ago that the Finnish researchers first identified a change affecting a single alkali in the human genome related to primary lactose malabsorption. The change is the conversion of cytosine to thymidine (genotype C/T) and it makes a person tolerate lactose for the rest of his/her life. Without this genetic change (genotype C/C), the activity of the lactase enzyme in small intestine mucosa is reduced at the age of 5 to 12 years on average, causing a deterioration of lactose tolerance.
Published in January and conducted by researchers from the Universities of Helsinki and Kuopio and the National Public Health Institute, the study investigated the relation between the genotype associated with lactose malabsorption and the occurrence of bone fracture in the elderly. The study included 483 elderly people in the City of Vantaa – 377 women and 106 men – all over 85 years of age.
Paivi Lehtinen | alfa
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