Yale scientists report in the journal Nature that the "missing" genes for tRNA in an ancient parasite are made up by splicing together sequences in distant parts of the DNA genome.
The research led by Professor Dieter Söll in the Department of Molecular Biophysics and Biochemistry at Yale focuses on the most ancient organism with a known genome sequence. Nanoarchaeum equitans, is a member of a new phylogenetic kingdom in the Archaea containing organisms that are primitive, parasitic and extremophile, or notable for living in the most extreme environments.
Surprisingly, Sölls team found that, although the genome of Nanoarchaeum lacks several intact tRNA genes, functional forms of those tRNAs can be made by copying from two distant DNA sequences -- and joining them.
Janet Rettig Emanuel | EurekAlert!
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