Combinatorial drug therapies, effective for cancer and AIDS, show potential for Huntington’s and other neurodegenerative diseases
UC Irvine researchers have identified several promising drug compounds that when combined show the potential to treat Huntington’s disease.
In tests on fruit flies, Larry Marsh and Leslie Thompson found that combinatorial drug therapies developed from these compounds halted the brain-cell damage caused by the fatal, progressive neurodegenerative disorder. Such types of therapies have proven very effective in the treatment of other complex human diseases, like cancers and AIDS. And while any human benefits from this study are years off, the research provides the first evidence that a regimen of complementary drugs can treat Huntington’s. Study results appear this week in the early online edition of the Proceedings of the National Academy of Sciences.
Tom Vasich | EurekAlert!
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