Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Study To Save Dobermanns From Fatal Heart Disease

14.02.2005


Vets at the University of Liverpool are looking for Dobermann volunteers to participate in a research project to combat canine heart disease.




The dogs will take part in a screening programme to detect early signs of dilated cardiomyopathy (DCM), a heart condition that is particularly common in the breed.

The disease, which can affect dogs, cats and humans, causes the heart to become enlarged and weakened. Over a number of years the contraction of the heart begins to decline and the muscle becomes enlarged, but the dog’s owner may not detect any symptoms of the disease for some time. When the dog does show signs of heart failure the disease progresses rapidly and can kill the animal within weeks.


Veterinary Cardiologist, Nuala Summerfield, is leading the national screening programme for Dobermanns with DCM, in partnership with the Dobermann Breed Club. The hospital is looking to recruit 300 healthy dogs over three years old to participate in the programme, which will be run at veterinary centres across the UK.

A blood sample will be taken from each dog for a general health check and a part of this will be retained for DNA extraction and genetic analysis. An ultrasound of the heart will also be taken to measure the size of the individual heart chambers and to determine how well the heart is contracting. Data collected from the trials will be used to study the role of proteins and genetics in causing DCM.

Nuala explains: "It is important that we find treatments in the symptom-free stage, as once the dog begins to show outward signs of the disease, it is much more difficult to treat. Drug therapy used in the later stages of the disease has proved disappointing and therefore early routine screening tests will prove essential in saving lives of dogs with DCM".

"Currently very little is known about DCM in both domestic animals and human beings. Through this study we hope to form a more accurate picture of how the disease works and more importantly how we can prevent it".

"We aim to use this knowledge to identify if there are any genes involved in causing the disease, which will help scientists develop genetic tests to screen young dogs before the condition arises."

The national screening programme will be officially launched at the Midland Dobermann Club Open Show at Belper Leisure Centre, Derbyshire on Sunday, 20 February, where dog owners and breeders are invited to learn more about the disease and new research.

If you would like your dog to participate in the screening programme or attend the official launch please contact Carol Smith at the Dobermann Breed Club on 0115 932 1698.

The screening process will be free of charge, although participants will be asked to make a voluntary donation towards the programme.

Kate Spark | alfa
Further information:
http://www.liv.ac.uk

More articles from Life Sciences:

nachricht Unique genome architectures after fertilisation in single-cell embryos
30.03.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH

nachricht Transport of molecular motors into cilia
28.03.2017 | Aarhus University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

NASA laser communications to provide Orion faster connections

30.03.2017 | Physics and Astronomy

Reusable carbon nanotubes could be the water filter of the future, says RIT study

30.03.2017 | Studies and Analyses

Unique genome architectures after fertilisation in single-cell embryos

30.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>