Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Study To Save Dobermanns From Fatal Heart Disease

14.02.2005


Vets at the University of Liverpool are looking for Dobermann volunteers to participate in a research project to combat canine heart disease.




The dogs will take part in a screening programme to detect early signs of dilated cardiomyopathy (DCM), a heart condition that is particularly common in the breed.

The disease, which can affect dogs, cats and humans, causes the heart to become enlarged and weakened. Over a number of years the contraction of the heart begins to decline and the muscle becomes enlarged, but the dog’s owner may not detect any symptoms of the disease for some time. When the dog does show signs of heart failure the disease progresses rapidly and can kill the animal within weeks.


Veterinary Cardiologist, Nuala Summerfield, is leading the national screening programme for Dobermanns with DCM, in partnership with the Dobermann Breed Club. The hospital is looking to recruit 300 healthy dogs over three years old to participate in the programme, which will be run at veterinary centres across the UK.

A blood sample will be taken from each dog for a general health check and a part of this will be retained for DNA extraction and genetic analysis. An ultrasound of the heart will also be taken to measure the size of the individual heart chambers and to determine how well the heart is contracting. Data collected from the trials will be used to study the role of proteins and genetics in causing DCM.

Nuala explains: "It is important that we find treatments in the symptom-free stage, as once the dog begins to show outward signs of the disease, it is much more difficult to treat. Drug therapy used in the later stages of the disease has proved disappointing and therefore early routine screening tests will prove essential in saving lives of dogs with DCM".

"Currently very little is known about DCM in both domestic animals and human beings. Through this study we hope to form a more accurate picture of how the disease works and more importantly how we can prevent it".

"We aim to use this knowledge to identify if there are any genes involved in causing the disease, which will help scientists develop genetic tests to screen young dogs before the condition arises."

The national screening programme will be officially launched at the Midland Dobermann Club Open Show at Belper Leisure Centre, Derbyshire on Sunday, 20 February, where dog owners and breeders are invited to learn more about the disease and new research.

If you would like your dog to participate in the screening programme or attend the official launch please contact Carol Smith at the Dobermann Breed Club on 0115 932 1698.

The screening process will be free of charge, although participants will be asked to make a voluntary donation towards the programme.

Kate Spark | alfa
Further information:
http://www.liv.ac.uk

More articles from Life Sciences:

nachricht Modern genetic sequencing tools give clearer picture of how corals are related
17.08.2017 | University of Washington

nachricht The irresistible fragrance of dying vinegar flies
16.08.2017 | Max-Planck-Institut für chemische Ökologie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Gold shines through properties of nano biosensors

17.08.2017 | Physics and Astronomy

Greenland ice flow likely to speed up: New data assert glaciers move over sediment, which gets more slippery as it gets wetter

17.08.2017 | Earth Sciences

Mars 2020 mission to use smart methods to seek signs of past life

17.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>