A compound may improve the chances that stem cells transplanted from a patient’s bone marrow will help take over brain functions
A compound similar to the components of DNA may improve the chances that stem cells transplanted from a patients bone marrow to the brain will take over the functions of damaged cells and help treat Alzheimers disease and other neurological illnesses.
A research team led by University of Central Florida professor Kiminobu Sugaya found that treating bone marrow cells in laboratory cultures with bromodeoxyuridine, a compound that becomes part of DNA, made adult human stem cells more likely to develop as brain cells after they were implanted in adult rat brains. The findings will be included in the next issue of the Restorative Neurology and Neuroscience journal, which is scheduled to be published in late February.
Sugaya and his colleagues at UCFs Burnett College of Biomedical Sciences hope to eventually show that stem cells transplanted from a patients blood or bone marrow will be an effective treatment for Alzheimers and other neurological diseases because they can replace cells that die from those ailments. The researchers are working with a $1.4 million grant from the National Institutes of Health.
Chad Binette | EurekAlert!
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