While large-scale genomic sequencing technologies over the past decade have given scientists databases filled with the complete genomes of hundreds of organisms, not enough is being done to interpret all that data by assigning functions to sequenced genes (annotation), according to a report released today by the American Academy of Microbiology. An Experimental Approach to Genome Annotation proposes a new initiative to help address this challenge.
"Roughly 40% of predicted genes have not been assigned even tentative functions. It is rare in science to be able to clearly delineate the boundaries of current knowledge, but that is exactly where genomics stands today," according to the report. "The annotation initiative proposed in this document will extend those boundaries and will likely lead to new applications and new progress in healthcare, biodefense, energy, the environment and agriculture."
Given the current lack of a reliable source of functional annotation data, the report recommends that a centralized genome annotation initiative be established in the United States. A key component of this initiative is the development of a centrally organized database of peer-reviewed, experimentally verified gene annotations, tied to catalogs of genes that have yet to be annotated and known biochemical functions for which a gene has yet to be found.
Polymers Based on Boron?
18.01.2018 | Julius-Maximilians-Universität Würzburg
Bioengineered soft microfibers improve T-cell production
18.01.2018 | Columbia University School of Engineering and Applied Science
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
18.01.2018 | Earth Sciences
18.01.2018 | Business and Finance
18.01.2018 | Medical Engineering