Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

19.01.2005


Made-to-measure skin and bones, which could be used to treat burn victims or patients who have suffered severe disfigurements, may soon be a reality using inkjets which can print human cells.



Scientists at The University of Manchester have developed the breakthrough technology which will allow tailor-made tissues and bones to be grown, simply by inputting their dimensions into a computer.

Professor Brian Derby, Head of the Ink-Jet Printing of Human Cells Project research team, said: “It is difficult for a surgeon to reconstruct any complex disfiguring of the face using CT scans, but with this technology we are able to build a fragment which will fit exactly. We can place cells in any designed position in order to grow tissue or bone.”


This breakthrough overcomes problems currently faced by scientists who are unable to grow large tissues and have limited control over the shape or size the tissue will grow to. It also allows more than one type of cell to be printed at once, which opens up the possibility of being able to create bone grafts. “Using conventional methods, you are only able to grow tissues which are a few millimetres thick, which is fine for growing artificial skin, but if you wanted to grow cartilage, for instance, it would be impossible,” Professor Derby says.

The key to the advance which Professor Derby and his team have made is the innovative way in which they are able to pre-determine the size and shape of the tissue or bone grown.

Using the printers, they are able create 3-dimensional structures, known as ‘tissue scaffolds’. The shape of the scaffold determines the shape of the tissue as it grows. The structures are created by printing very thin layers of a material repeatedly on top of each other until the structure is built. Each layer is just 10 microns thick (1,000 layers equals 1cm in thickness).

This method allows larger tissues to be grown than previously possible. The reason for this is the way in which the cells are inserted into the structures.

Before being fed into the printer, the cells are suspended in a nutrient rich liquid not dissimilar to ink, which ensures their survival. The cells are then fed into the printer and seeded directly into the structure as it is built. This avoids any ‘sticking to the surface’ which is a major disadvantage of current methods that infuse the cells into the structure after it has been built.

“The problem is getting cells into the interior of these constructions as they naturally stick to the sides of whatever they are being inserted into. If they stick to the sides then this limits the number of cells which can grow into tissues, and the lack of penetration also limits their size. By using inkjet printing we are able to seed the cells into the construction as we build it, which means ‘sticking’ isn’t a problem,” says Professor Derby.

Professor Derby believes the potential for this technology is huge: “You could print the scaffolding to create an organ in a day,” he says.

Simon Hunter | alfa
Further information:
http://www.manchester.ac.uk

More articles from Life Sciences:

nachricht The birth of a new protein
20.10.2017 | University of Arizona

nachricht Building New Moss Factories
20.10.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>