Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

19.01.2005


Made-to-measure skin and bones, which could be used to treat burn victims or patients who have suffered severe disfigurements, may soon be a reality using inkjets which can print human cells.



Scientists at The University of Manchester have developed the breakthrough technology which will allow tailor-made tissues and bones to be grown, simply by inputting their dimensions into a computer.

Professor Brian Derby, Head of the Ink-Jet Printing of Human Cells Project research team, said: “It is difficult for a surgeon to reconstruct any complex disfiguring of the face using CT scans, but with this technology we are able to build a fragment which will fit exactly. We can place cells in any designed position in order to grow tissue or bone.”


This breakthrough overcomes problems currently faced by scientists who are unable to grow large tissues and have limited control over the shape or size the tissue will grow to. It also allows more than one type of cell to be printed at once, which opens up the possibility of being able to create bone grafts. “Using conventional methods, you are only able to grow tissues which are a few millimetres thick, which is fine for growing artificial skin, but if you wanted to grow cartilage, for instance, it would be impossible,” Professor Derby says.

The key to the advance which Professor Derby and his team have made is the innovative way in which they are able to pre-determine the size and shape of the tissue or bone grown.

Using the printers, they are able create 3-dimensional structures, known as ‘tissue scaffolds’. The shape of the scaffold determines the shape of the tissue as it grows. The structures are created by printing very thin layers of a material repeatedly on top of each other until the structure is built. Each layer is just 10 microns thick (1,000 layers equals 1cm in thickness).

This method allows larger tissues to be grown than previously possible. The reason for this is the way in which the cells are inserted into the structures.

Before being fed into the printer, the cells are suspended in a nutrient rich liquid not dissimilar to ink, which ensures their survival. The cells are then fed into the printer and seeded directly into the structure as it is built. This avoids any ‘sticking to the surface’ which is a major disadvantage of current methods that infuse the cells into the structure after it has been built.

“The problem is getting cells into the interior of these constructions as they naturally stick to the sides of whatever they are being inserted into. If they stick to the sides then this limits the number of cells which can grow into tissues, and the lack of penetration also limits their size. By using inkjet printing we are able to seed the cells into the construction as we build it, which means ‘sticking’ isn’t a problem,” says Professor Derby.

Professor Derby believes the potential for this technology is huge: “You could print the scaffolding to create an organ in a day,” he says.

Simon Hunter | alfa
Further information:
http://www.manchester.ac.uk

More articles from Life Sciences:

nachricht Flavins keep a handy helper in their pocket
25.04.2018 | University of Freiburg

nachricht Complete skin regeneration system of fish unraveled
24.04.2018 | Tokyo Institute of Technology

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: BAM@Hannover Messe: innovative 3D printing method for space flight

At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.

Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...

Im Focus: Molecules Brilliantly Illuminated

Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.

Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...

Im Focus: Spider silk key to new bone-fixing composite

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Getting electrons to move in a semiconductor

25.04.2018 | Physics and Astronomy

Reconstructing what makes us tick

25.04.2018 | Physics and Astronomy

Cheap 3-D printer can produce self-folding materials

25.04.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>