Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

19.01.2005


Made-to-measure skin and bones, which could be used to treat burn victims or patients who have suffered severe disfigurements, may soon be a reality using inkjets which can print human cells.



Scientists at The University of Manchester have developed the breakthrough technology which will allow tailor-made tissues and bones to be grown, simply by inputting their dimensions into a computer.

Professor Brian Derby, Head of the Ink-Jet Printing of Human Cells Project research team, said: “It is difficult for a surgeon to reconstruct any complex disfiguring of the face using CT scans, but with this technology we are able to build a fragment which will fit exactly. We can place cells in any designed position in order to grow tissue or bone.”


This breakthrough overcomes problems currently faced by scientists who are unable to grow large tissues and have limited control over the shape or size the tissue will grow to. It also allows more than one type of cell to be printed at once, which opens up the possibility of being able to create bone grafts. “Using conventional methods, you are only able to grow tissues which are a few millimetres thick, which is fine for growing artificial skin, but if you wanted to grow cartilage, for instance, it would be impossible,” Professor Derby says.

The key to the advance which Professor Derby and his team have made is the innovative way in which they are able to pre-determine the size and shape of the tissue or bone grown.

Using the printers, they are able create 3-dimensional structures, known as ‘tissue scaffolds’. The shape of the scaffold determines the shape of the tissue as it grows. The structures are created by printing very thin layers of a material repeatedly on top of each other until the structure is built. Each layer is just 10 microns thick (1,000 layers equals 1cm in thickness).

This method allows larger tissues to be grown than previously possible. The reason for this is the way in which the cells are inserted into the structures.

Before being fed into the printer, the cells are suspended in a nutrient rich liquid not dissimilar to ink, which ensures their survival. The cells are then fed into the printer and seeded directly into the structure as it is built. This avoids any ‘sticking to the surface’ which is a major disadvantage of current methods that infuse the cells into the structure after it has been built.

“The problem is getting cells into the interior of these constructions as they naturally stick to the sides of whatever they are being inserted into. If they stick to the sides then this limits the number of cells which can grow into tissues, and the lack of penetration also limits their size. By using inkjet printing we are able to seed the cells into the construction as we build it, which means ‘sticking’ isn’t a problem,” says Professor Derby.

Professor Derby believes the potential for this technology is huge: “You could print the scaffolding to create an organ in a day,” he says.

Simon Hunter | alfa
Further information:
http://www.manchester.ac.uk

More articles from Life Sciences:

nachricht For a chimpanzee, one good turn deserves another
27.06.2017 | Max-Planck-Institut für Mathematik in den Naturwissenschaften (MPIMIS)

nachricht New method to rapidly map the 'social networks' of proteins
27.06.2017 | Salk Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Ultra-compact phase modulators based on graphene plasmons

27.06.2017 | Physics and Astronomy

For a chimpanzee, one good turn deserves another

27.06.2017 | Life Sciences

Collapse of the European ice sheet caused chaos

27.06.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>