The bacterium that causes the severe disease known as rabbit fever, Fancisella tularensis, is a potential biological weapon of devastating force. Now scientists at Umeå, in collaboration with several international associates, have mapped the entire genome of the bacterium.
Researchers at the Swedish Defense Research Agency FOI NBC Defense and Umeå University are part of an international consortium that is now publishing its results in the prestigious journal Nature Genetics. The article is a report from the charting of the complete DNA sequence of the bacterium, so-called sequencing, and the study of the genome of a fully pathogenic strain of Francisella tularensis. The genome consists of nearly 1.9 billion base pairs, among which the scientists have managed to find 1,804 genes.
The functional description of the genome presents the pathogenic properties of the bacterium, including the formation of so-called pili, a type of projection that is used in infecting human cells. Another property described is the ability of the bacterium to absorb iron, a feature that is necessary for the bacterium to be able to bring about disease.
Bertil Born | alfa
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