Fox Chase Cancer Center researchers have made new discoveries that shed new light on the mystery of why human tissues, such as skin, age. The findings focus on the composition and assembly of key chromosomal protein complexes involved in shutting down reproduction of aging cells. The report by molecular and cell biologist Peter D. Adams, Ph.D. and his colleagues appears in the January 2005 issue of Developmental Cell.
"In the lab, aging cells are called senescent cells. Senescent cells are no longer able to divide but remain metabolically active," Adams explained. "Accumulation of senescent cells over time appears to contribute to changes in tissue form and function commonly associated with aging, like the skin changes that occur between childhood and old age."
Most normal human cells undergo a limited number of cell divisions but are eventually arrested, either through final differentiation or senescence. Differentiation is the process whereby a proliferating cell stops growing and develops into a cell with a specific function, such as a liver cell or a neuron. Senescence is an irreversible stage in a cells life cycle and may underlie the human aging process and have an impact on diseases of aging, such as adult cancers.
Karen C. Mallet | EurekAlert!
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09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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