Fox Chase Cancer Center researchers have made new discoveries that shed new light on the mystery of why human tissues, such as skin, age. The findings focus on the composition and assembly of key chromosomal protein complexes involved in shutting down reproduction of aging cells. The report by molecular and cell biologist Peter D. Adams, Ph.D. and his colleagues appears in the January 2005 issue of Developmental Cell.
"In the lab, aging cells are called senescent cells. Senescent cells are no longer able to divide but remain metabolically active," Adams explained. "Accumulation of senescent cells over time appears to contribute to changes in tissue form and function commonly associated with aging, like the skin changes that occur between childhood and old age."
Most normal human cells undergo a limited number of cell divisions but are eventually arrested, either through final differentiation or senescence. Differentiation is the process whereby a proliferating cell stops growing and develops into a cell with a specific function, such as a liver cell or a neuron. Senescence is an irreversible stage in a cells life cycle and may underlie the human aging process and have an impact on diseases of aging, such as adult cancers.
Karen C. Mallet | EurekAlert!
Cancer diagnosis: no more needles?
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A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
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At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
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There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
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