Immune cells can trigger severe pneumonia
A new study has found that malfunctioning immune cells can be the cause of severe pneumonia. This discovery was made by scientists working at the German Research Centre for Biotechnology (GBF) in Braunschweig. In the latest issue of the American Journal of Respiratory and Critical Care Medicine (AJRCCM), GBF researchers describe how mice in their experiments developed a tendency toward chronic inflammation of the lung’s mucous membrane. What they found was that immune cells of the type known as CD 4+T cells bring on such a disease when they inadvertently attack the body’s own tissue instead of the invading pathogen.
Diseases and disruptions to pulmonary alveoli and the lung, lymph and vascular tissues of the respiratory system are termed “Interstitial Lung Disease” (ILD) by the medical profession. Various forms of pneumonia are also classified under the ILD heading and can afflict mice as well as humans. The GBF research group led by Professor Jan Buer working together with colleagues from Yale University in the USA used these mice to prove something scientists had long suspected but until now had been unable to prove: that malfunctioning CD 4+T cells play an active role in the emergence of many forms of ILD.
Manfred Braun | alfa
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