Scientists use fluorescence to track ultrafine particles taken up by white blood cells
In some of the first work documenting the uptake of carbon nanotubes by living cells, a team of chemists and life scientists from Rice University, the University of Texas Health Science Center at Houston and the Texas Heart Institute have selectively detected low concentrations of nanotubes in laboratory cell cultures.
The research appears in the Dec. 8 issue of the Journal of the American Chemical Society. It suggests that the white blood cells, which were incubated in dilute solutions of nanotubes, treated the nanotubes as they would other extracellular particles – actively ingesting them and sealing them off inside chambers known as phagosomes. "Our goal in doing the experiment was both to learn how the biological function of the cells was affected by the nanotubes and to see if the fluorescent properties of the nanotubes would change inside a living cell," said lead researcher Bruce Weisman, professor of chemistry at Rice. "On the first point, we found no adverse effects on the cells, and on the second, we found that the nanotubes retained their unique optical properties, which allowed us to use a specialized microscope tuned to the near-infrared to pinpoint their locations within the cells."
Jade Boyd | EurekAlert!
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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