Scientists at The Wistar Institute, working in collaboration with colleagues at the University of Helsinki, have discovered structural similarities among viruses that infect hosts from all three domains of life. These structural similarities suggest that the viruses, despite their genomic variations and differences in hosts, may have evolved from a common ancestor billions of years ago. The findings will be published in the December 3 issue of Molecular Cell.
Until recently, scientists have tended to view the viral universe as unrelated families of viruses, with little attention given to their similarities. "People tended to concentrate on a single type of virus," says Roger M. Burnett, Ph.D., senior author of the study and professor in Wistars immunology program. "It hadnt been appreciated until a few years ago that there are great structural similarities among seemingly unrelated viruses."
The research builds on earlier work by Burnett and his colleagues, in which they determined the structure of a virus called PRD1 that infects bacteria. They found that it has remarkable structural similarities to human adenoviruses, which cause various diseases, including respiratory infections. Using data from their own and other laboratories, the researchers have created structure-based models to demonstrate structural similarities in the coats--proteins and architecture--among viruses that infect hosts from all three domains of life. The three domains are eukarya (animals, plants, and other higher order organisms); bacteria; and archaea (a recently described group of microorganisms that differ from bacteria and are commonly found in extreme environments like geysers, and alkaline, acidic or salty waters).
Franklin Hoke | EurekAlert!
Water forms 'spine of hydration' around DNA, group finds
26.05.2017 | Cornell University
How herpesviruses win the footrace against the immune system
26.05.2017 | Helmholtz-Zentrum für Infektionsforschung
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy