A gene hunt being carried out at the University of Leicester for a skin disorder that affects over one million people in the UK alone has made a new breakthrough which could lead to the design of new and more targeted drugs.
The research team in the University of Leicester Division of Medical Genetics, led by Professor Richard Trembath, has been investigating Psoriasis - an inflammatory skin condition - for a number of years. Now Professor Trembath believes the research has made a ‘significant step’ towards understanding the causes of psoriasis by discovering detailed genetic differences in those afflicted with the disorder.
He said: “In individuals that are genetically predisposed to become affected, the disease can be triggered by a number of environmental agents, such as bacterial infections or stress. We have long been engaged in the search for genes that make people vulnerable to the action of psoriasis-triggering factors. “Our past studies have demonstrated that a small region of what is known as Chromosome 6 contained at least one of such psoriasis susceptibility genes. A closer examination of this genetic interval identified a gene called CDSN, responsible for the adhesion and shedding of skin cells.
Ather Mirza | alfa
Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH
Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences