Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers within sight of a breakthrough on blindness

04.11.2004


The discovery by a Leeds University scientist of a new blindness gene could help to save the sight of thousands of sufferers of retinal disease which affects premature babies as well as people over 60.



By improving our understanding of vascular development, the breakthrough could also shed light on other diseases including tumour formation and arthritis. Carmel Toomes, member of the Leeds vision research group, said the work could lead to early diagnosis of diseases affecting the light-sensitive part of the eye which cause the majority of cases of blindness and visual disability in the UK.

Thanks to her gene discovery, Dr Toomes has begun a Royal Society research fellowship which will enable her to continue the research for at least another five years. “The effects of blindness can be devastating,” she said. “It is very frightening to imagine how your life would change if you were to lose your sight, but for many this is a reality. By the time we retire, one in 50 of us will have a significant defect of vision and after retirement the incidence rises sharply.”


Although retinal disease is mostly untreatable, and sight can rarely be restored once vision loss has occurred, it can sometimes be prevented if a patient is diagnosed early enough. Dr Toomes is using genetics to understand the disease. While there are many different causes for the various types of retinal blindness, the cellular processes involved are often similar.

The group is studying rare inherited forms of retinal disease in order to understand the more common forms of blindness affected by the growth of abnormal blood vessels in diabetic retinopathy and ageing-macular dystrophy – the leading causes of blindness in the western world. The research should lead to the development of new treatments for these conditions.

The discovery of the new blindness gene was reported in the American Journal of Human Genetics.

Vanessa Bridge | alfa
Further information:
http://www.leeds.ac.uk

More articles from Life Sciences:

nachricht Toward a 'smart' patch that automatically delivers insulin when needed
18.01.2017 | American Chemical Society

nachricht 127 at one blow...
18.01.2017 | Stiftung Zoologisches Forschungsmuseum Alexander Koenig, Leibniz-Institut für Biodiversität der Tiere

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

A big nano boost for solar cells

18.01.2017 | Power and Electrical Engineering

Glass's off-kilter harmonies

18.01.2017 | Materials Sciences

Toward a 'smart' patch that automatically delivers insulin when needed

18.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>