Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study reveals genetic link to colon cancer

03.11.2004


Mutation indicates risk of acquiring disease



Researchers from the Samuel Lunenfeld Research Institute at Mount Sinai Hospital have determined that the mutation of a specific gene in some patients with colon cancer indicate a risk of acquiring the disease. The study appears in the Nov. 3 edition of the Journal of the National Cancer Institute. The research team, led by Dr. Steven Gallinger used a population based study to determine that when one parent had the MutY human homologue (MYH) gene and there was also a family history of acquiring the disease then it may account for a fraction of hereditary colorectal cancers.

The child of a couple that has one MYH gene carrier has a 1:2 risk of carrying the mutation and this translates into increased risk of developing the disease. "This is going to contribute to new knowledge of colon cancer and it may impact who goes for testing," said Dr. Gallinger, a researcher and surgeon. He is also a professor of surgery at the University of Toronto.


The study suggests this information to be used in the identification of potential high risk cases to see if screening and further testing of the patient and family members is required. This research builds on previous studies that suggest the child of a couple where both parents are carriers has a 1:4 chance of developing a severe form of colon cancer. As many as 20 per cent of colorectal cancer patients have a family history of the disease.

The population based study followed 1238 patients with colorectal cancer and 1255 healthy control subjects from Ontario. Compared to non-carriers, the MYH gene carriers had a higher risk of acquiring colorectal cancer.

Kathy Pyatt | EurekAlert!
Further information:
http://www.utoronto.ca

More articles from Life Sciences:

nachricht Cancer diagnosis: no more needles?
25.05.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Less is more? Gene switch for healthy aging found
25.05.2018 | Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>